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Three aspects of genetics are covered: 1) Mechanisms of gene transmission, including chromosome mapping and genetic pathways; 2) Mutational analysis of biological processes with an emphasis on mutations that affect chromosome transmission; 3) An introduction to genomics--the cloning and sequence analysis of whole genomes. The emphasis is on both formal genetic mechanisms and molecular techniques. The development of recombinant DNA technologies has resulted in an explosion of new ideas and laboratory techniques in the realm of molecular biology. This course is very “lab heavy”. Students will develop their lab techniques with the following investigations: 1) Biochemistry related to the nature of DNA structure and function 2) Gene expression and regulation 3) DNA extraction and analysis 4) Horizontal and vertical gel electrophoresis 5) DNA amplification (PCR) techniques 6) Mitochondrial DNA extraction 7) Genetically Modified Organisms (GMO) investigations 8) Protein gel electrophoresis and proteomics 9) Genomics information The last quarter will investigate the patterns and processes of evolution. The following topics will be covered: natural selection, population genetics, macroevolution and microevolution, human evolution and biodiversity. |
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